SCHEMBL11683056

SCHEMBL11683056

CN(CCCCS(=O)(=O)O)S(=O)(=O)c1cc(Cl)c(N)cc1Cl

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
THRB P10828 3/20 0.38
GSTO1 P78417 4/20 0.38
VCAM1 P19320 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.36
HTR4 Q13639 2/20 0.35
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
CYP3A4 P08684 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11682730 0.96 ALDH1A1 (0.47) ALDH1A1THRBGSTO1VCAM1L3MBTL1
SCHEMBL10692557 0.91 ALDH1A1 (0.49) ALDH1A1THRBGSTO1VCAM1L3MBTL1
SCHEMBL11521525 0.79 ALDH1A1 (0.46) ALDH1A1THRBGSTO1L3MBTL1HTR4
SCHEMBL11518719 0.77 ALDH1A1 (0.43) ALDH1A1HTR4CA12CA1CA2
SCHEMBL11681244 0.76 ALDH1A1 (0.42) ALDH1A1THRBVCAM1L3MBTL1CA12
SCHEMBL11516387 0.76 ALDH1A1 (0.46) ALDH1A1THRBL3MBTL1HTR4CA12
SCHEMBL3844818 0.74 VCAM1 (0.46) ALDH1A1THRBVCAM1KMT2ASMN1; SMN2
SCHEMBL11683847 0.74 VCAM1 (0.43) ALDH1A1THRBGSTO1VCAM1L3MBTL1
SCHEMBL11683784 0.74 KMT2A (0.40) ALDH1A1THRBGSTO1HTR4CYP3A4
SCHEMBL10687962 0.73 ALDH1A1 (0.47) ALDH1A1THRBVCAM1L3MBTL1CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed