SCHEMBL11683094 — predicted protein targets

Predicted protein targets (top 14)

	gene	UniProt	supporting neighbours	confidence
▸	TDP1	Q9NUW8	2/20	0.53

▸	MEN1	O00255	8/20	0.52

▸	KMT2A	Q03164	8/20	0.52

▸	ALDH1A1	P00352	4/20	0.52

▸	LMNA	P02545	3/20	0.52

▸	MAPT	P10636	2/20	0.52

▸	SMN1; SMN2	Q16637	1/20	0.52

▸	CYP3A4	P08684	1/20	0.49

▸	TSHR	P16473	1/20	0.49

▸	GAA	P10253	1/20	0.47

▸	PKM	P14618	1/20	0.47

▸	POLB	P06746	1/20	0.47

▸	HPGD	P15428	1/20	0.47

▸	NPSR1	Q6W5P4	1/20	0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11690054	0.90	TDP1 (0.57)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL11683221	0.88	BRAF (0.53)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL11683829	0.84	ALDH1A1 (0.60)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL5533137	0.84	MEN1 (0.57)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL10792602	0.81	TDP1 (0.78)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL1679963	0.78	TDP1 (0.64)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL1679893	0.78	TDP1 (0.71)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL10246421	0.75	MEN1 (0.59)	MEN1KMT2AALDH1A1LMNAMAPT
SCHEMBL9677406	0.74	TDP1 (0.83)	TDP1MEN1KMT2AALDH1A1LMNA
SCHEMBL27193219	0.74	MAPT (0.52)	TDP1MEN1KMT2AALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4056522-A	PIGMENTS	HOECHST AKTIENGESELLSCHAFT (DT)	1977-11-01	—	—	US	disclosed
US-4056553-A	INTERMEDIATES FOR MONOAZO DYES	HOECHST AKTIENGESELLSCHAFT (DT)	1977-11-01	—	—	US	disclosed