Cyclohexane

Cyclohexane

SCHEMBL11683239

C1CCCCC1.ClC(Cl)(Cl)Cl.ClCCl

nearest known ligand 0.40

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Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
CYP2E1 P05181 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclopentane SCHEMBL29088065 0.84
Cyclohexane SCHEMBL5712062 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclohexane SCHEMBL12476090 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclohexane SCHEMBL12475625 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclohexane SCHEMBL3212439 0.84 TSHR (0.57) ALDH1A1LMNACYP2E1TSHR
Cyclohexane SCHEMBL185456 0.84
Carbon Tetrachloride SCHEMBL1405331 0.84
Cyclohexane SCHEMBL12475806 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclohexane SCHEMBL21879029 0.84 ALDH1A1 (0.57) ALDH1A1TSHR
Cyclohexane SCHEMBL11489570 0.84 ALDH1A1 (0.57) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002682-A CHEMICAL INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-01-11 US disclosed
US-3952044-A INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-04-20 US disclosed