Cyclohexane

Cyclohexane

SCHEMBL3212439

C1CCCCC1.ClC(Cl)(Cl)Cl

nearest known ligand 0.57

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.57
ALDH1A1 P00352 1/20 0.57
LMNA P02545 1/20 0.57
CYP2E1 P05181 1/20 0.57
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cyclohexane SCHEMBL11684983 0.84 TSHR (0.40) TSHRALDH1A1LMNACYP2E1
Cyclohexane SCHEMBL11683239 0.84 ALDH1A1 (0.40) TSHRALDH1A1LMNACYP2E1
Cyclohexane SCHEMBL9151609 0.77
Cyclopropane SCHEMBL582029 0.77
Carbon Tetrachloride SCHEMBL100 0.76
Carbon Tetrachloride SCHEMBL8874630 0.76 TSHR (1.00) TSHRALDH1A1LMNACYP2E1
Carbon Tetrachloride SCHEMBL3648805 0.76
Carbon Tetrachloride SCHEMBL23174396 0.68
Carbon Tetrachloride SCHEMBL11209826 0.68
Carbon Tetrachloride SCHEMBL15413836 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0550875-B2 PROCESS FOR THE PRODUCTION OF AN IMPLANTABLE POLYMERIC DEVICE CONTAINING PHARMACEUTICAL AGENTS SCHIERHOLZ JOERG DR DR (DE) 2007-05-02 EP claimed
EP-0550875-B1 Implantable polymeric device containing pharmaceutical agents and process for its production SCHIERHOLZ JOERG DR DR (DE) 1998-04-29 EP claimed
US-4104363-A Method for preparation of perfectly spherical particles of silicagel with controlled size and controlled pore dimensions CESKOSLOVENSKA AKADEMIE VED (CS) 1978-08-01 US claimed
CN-115192517-A Multifoam and eyelid application thereof 参天制药股份有限公司 2022-10-18 CN disclosed
CN-107205929-B Multifoam and eyelid application thereof 参天制药股份有限公司 2022-06-24 CN disclosed
US-20180015166-A1 POLYAPHRONS AND PALPEBRAL ADMINISTRATION THEREOF SANTEN SAS (FR) 2018-01-18 US disclosed
CN-105517789-B laminated tube 宇部兴产株式会社 2017-10-17 CN disclosed
CN-107205929-A Multifoam and eyelid application thereof 参天制药股份有限公司 2017-09-26 CN disclosed
WO-2016124601-A1 POLYAPHRONS AND PALPEBRAL ADMINISTRATION THEREOF SANTEN PHARMACEUTICAL CO., LTD (JP) 2016-08-11 WO disclosed
CN-105133318-A Silicone-modified mudar floss oil absorption material UNIV LANZHOU 2015-12-09 CN disclosed
US-8734856-B2 Cell extract for cell-free protein synthesis and process for producing the same CELLFREE SCIENCES CO., LTD. (JP) 2014-05-27 US disclosed
US-4486333-A Preparation of biliquid foam compositions SEBBA FELIX (US) 1984-12-04 US disclosed
EP-0076030-A2 Substituted amide derivatives, processes for preparing them, pesticidal compositions containing them and processes for combating unwanted vegetation and fungi IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-04-06 EP disclosed
US-4342781-A PREVENTING AND TREATING ALLERGIC BRONCHIAL ASTHMA, RHINITIS AND SKIN DISORDERS PFIZER INC. (US) 1982-08-03 US disclosed
US-4335054-A Process for the preparation of alkenylbenzenecarboxylic acid derivatives and alkenylnaphthalenecarboxylic acid derivatives CIBA-GEIGY CORPORATION (US) 1982-06-15 US disclosed
US-4207107-A Novel ortho-quinone diazide photoresist sensitizers RCA CORPORATION (US) 1980-06-10 US disclosed
US-4007169-A ANTIBIOTIC ARCHIFAR INDUSTRIE CHIMICHE DEL TRENTINO S.P.A. (IT) 1977-02-08 US disclosed
US-4002682-A CHEMICAL INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-01-11 US disclosed
US-3952044-A INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-04-20 US disclosed
US-3950533-A Pyrocatechol carbamates and o-mercaptophenol carbamates and their use for combating pests CIBA-GEIGY AG (CH) 1976-04-13 US disclosed