Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.63 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.63 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.63 |
| ▸ | OPRL1 | P41146 | 5/20 | 0.63 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11685046 | 0.89 | OPRM1 (0.60) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL19475380 | 0.88 | OPRM1 (0.66) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL19717859 | 0.87 | OPRL1 (0.61) | OPRM1OPRD1OPRK1OPRL1CYP3A4 | |
| SCHEMBL11682701 | 0.86 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL614227 | 0.83 | OPRM1 (0.68) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL11683633 | 0.81 | OPRM1 (0.56) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL10607282 | 0.79 | OPRM1 (0.61) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL3018551 | 0.75 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL7848116 | 0.75 | OPRM1 (0.57) | OPRM1OPRD1OPRK1OPRL1DRD3 | |
| SCHEMBL7312114 | 0.75 | OPRM1 (0.51) | OPRM1OPRD1OPRK1OPRL1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061760-A | Method for using 3-substituted-5-phenyl-5-pyridyl hydantoins as antiarrhythmic agents | MILES LABORATORIES, INC. (US) | 1977-12-06 | — | — | US | disclosed |
| US-3994904-A | 3-Substituted -5-phenyl-5-pyridyl hydantoins | MILES LABORATORIES, INC. (US) | 1976-11-30 | — | — | US | disclosed |