Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
| ▸ | DRD5 | P21918 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11683414 | 0.81 | DRD1 (0.42) | SRD5A1DRD1DRD2DRD4DRD5 | |
| SCHEMBL6565814 | 0.71 | SRD5A1 (0.52) | SRD5A1CYP19A1DRD2DRD3HSD17B1 | |
| SCHEMBL6247266 | 0.71 | SRD5A1 (0.52) | SRD5A1CYP19A1DRD2DRD3HSD17B1 | |
| SCHEMBL6247040 | 0.71 | SRD5A1 (0.52) | SRD5A1CYP19A1DRD2DRD3HSD17B1 | |
| SCHEMBL8169377 | 0.69 | SRD5A1 (0.63) | SRD5A1 | |
| SCHEMBL8169380 | 0.69 | SRD5A1 (0.63) | SRD5A1 | |
| SCHEMBL29795180 | 0.69 | DRD1 (0.64) | DRD1DRD2DRD4DRD5DRD3 | |
| SCHEMBL9748795 | 0.67 | DRD1 (0.48) | SRD5A1DRD1DRD2DRD4DRD5 | |
| SCHEMBL9748787 | 0.67 | DRD1 (0.48) | SRD5A1DRD1DRD2DRD4DRD5 | |
| SCHEMBL9748779 | 0.67 | DRD1 (0.48) | SRD5A1DRD1DRD2DRD4DRD5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064177-A | 3-Alkoxy-D-homo-C-nor-13α, 14α-gona-1,3,5,(10),6,8-pentaen-17-one and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-12-20 | — | — | US | disclosed |