Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169380 | 1.00 | SRD5A1 (0.63) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL1884010 | 0.78 | HSD11B1 (0.80) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL1884009 | 0.78 | HSD11B1 (0.80) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL15139435 | 0.78 | HSD11B1 (0.80) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL9964011 | 0.78 | HSD11B1 (0.80) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL7797807 | 0.77 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL7797809 | 0.77 | SRD5A1 (1.00) | SRD5A1 | |
| SCHEMBL8168469 | 0.77 | HTR1A (0.58) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL8172160 | 0.77 | HTR1A (0.58) | SRD5A1SIGMAR1HSD11B1 | |
| SCHEMBL8172163 | 0.77 | HTR1A (0.58) | SRD5A1SIGMAR1HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080752-A | FOR TREATING CONDITION WHICH REQUIRES ANTAGONISM OF A DOPAMINE RECEPTOR SUCH AS PSYCHTIC CONDITION | SMITHKLINE BEECHAM PLC (GB) | 2000-06-27 | — | — | US | disclosed |