Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 2/20 | 0.52 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6247266 | 1.00 | SRD5A1 (0.52) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6247040 | 1.00 | SRD5A1 (0.52) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6260285 | 0.74 | SRD5A1 (0.55) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6249634 | 0.74 | SRD5A1 (0.55) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6851908 | 0.72 | LMNA (0.55) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6568982 | 0.72 | LMNA (0.55) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL6569001 | 0.71 | LMNA (0.60) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL25529639 | 0.71 | LMNA (0.60) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL11684200 | 0.71 | SRD5A1 (0.46) | SRD5A1HSD17B1LMNAMAPTRECQL | |
| SCHEMBL7797824 | 0.69 | SRD5A1 (0.65) | SRD5A1HSD17B1LMNAMAPTRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002053522-A2 | NOVEL ESTROGEN RECEPTOR LIGANDS AND METHODS I | KARO BIO AB (SE) | 2002-07-11 | — | — | WO | disclosed |