SCHEMBL11684273

SCHEMBL11684273

CCN(CCOc1ccccc1)Cc1ccc(C)cc1

nearest known ligand 0.66

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.61
LTA4H P09960 1/20 0.61
CYP2D6 P10635 1/20 0.61
CYP2C9 P11712 1/20 0.61
CYP2C19 P33261 1/20 0.61
HTT P42858 1/20 0.61
MAOB P27338 1/20 0.52
EBP Q15125 1/20 0.49
SIGMAR1 Q99720 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11684281 0.94 CYP1A2 (0.66) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL11682494 0.87 BCHE (0.52) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL12610941 0.82 CYP2D6 (0.74) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL1405290 0.82 CYP2D6 (0.74) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL11681701 0.81 TSHR (0.68) LTA4HMAOB
SCHEMBL11682505 0.81 BCHE (0.55) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL13407333 0.81 POLB (0.51) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL8790159 0.81 CYP1A2 (0.64) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
SCHEMBL9112270 0.80 LTA4H (0.57) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL10505479 0.80 CYP2D6 (0.72) CYP1A2LTA4HCYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4041024-A FOR POLYAMIDES AND POLYURETHANES BAYER AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed