SCHEMBL12610941

SCHEMBL12610941

CCN(CC)CCOc1ccccc1.CCN(CC)CCOc1ccccc1

nearest known ligand 0.74

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.74
HTT P42858 2/20 0.74
LTA4H P09960 2/20 0.74
CYP1A2 P05177 1/20 0.74
CYP2C9 P11712 1/20 0.74
CYP2C19 P33261 1/20 0.74
EBP Q15125 3/20 0.62
SIGMAR1 Q99720 3/20 0.62
ESR1 P03372 3/20 0.62
DRD3 P35462 3/20 0.62
KMT2A Q03164 3/20 0.62
KCNH2 Q12809 2/20 0.62
CHRM2 P08172 2/20 0.62
ADRA2A P08913 2/20 0.62
ADORA3 P0DMS8 2/20 0.62
CHRM1 P11229 2/20 0.62
PTGS1 P23219 2/20 0.62
SLC6A2 P23975 2/20 0.62
SLC6A4 P31645 2/20 0.62
HTR6 P50406 2/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1405290 1.00 CYP2D6 (0.74) CYP2D6HTTLTA4HCYP1A2CYP2C9
Bromide SCHEMBL1173547 0.98 CYP2D6 (0.72) CYP2D6HTTLTA4HCYP1A2CYP2C9
Hydrochloric Acid SCHEMBL10505479 0.98 CYP2D6 (0.72) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL6676718 0.90 LTA4H (0.62) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL9706125 0.89 EBP (0.72) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL21195812 0.87 KCNA3 (0.64) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL22224170 0.86 ALDH1A1 (0.63) CYP2D6HTTLTA4HCYP1A2CYP2C9
Methylamine SCHEMBL10666826 0.86 LTA4H (0.58) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL14463907 0.86 LTA4H (0.57) CYP2D6HTTLTA4HCYP1A2CYP2C9
SCHEMBL9706141 0.86 KDM4E (0.73) CYP2D6HTTLTA4HCYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2688878-A1 PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES SANOFI (FR) 2014-01-29 EP disclosed
WO-2012127173-A1 PROCESS FOR SYNTHESIZING KETO-BENZOFURAN DERIVATIVES SANOFI (FR) 2012-09-27 WO disclosed