Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10702274 | 0.78 | TSHR (0.50) | ABL1LMNARIN1TSHRGSK3A | |
| SCHEMBL8461039 | 0.75 | MEN1 (0.51) | ABL1LMNARIN1TSHRALDH1A1 | |
| SCHEMBL2527934 | 0.74 | — | — | |
| SCHEMBL8991932 | 0.74 | MEN1 (0.40) | ABL1LMNARIN1TSHRALDH1A1 | |
| SCHEMBL839301 | 0.74 | TSHR (0.48) | ABL1LMNARIN1TSHRGSK3A | |
| Ammonia Solution, Strong SCHEMBL11623974 | 0.73 | TSHR (0.57) | ABL1LMNARIN1TSHRGSK3A | |
| SCHEMBL24737479 | 0.72 | ABL1 (0.43) | ABL1LMNARIN1TSHRGSK3A | |
| SCHEMBL1969772 | 0.71 | TSHR (0.55) | ABL1LMNARIN1TSHRGSK3A | |
| SCHEMBL29304531 | 0.71 | TSHR (0.46) | ABL1LMNARIN1TSHRGSK3A | |
| SCHEMBL1401795 | 0.68 | TSHR (0.52) | ABL1LMNARIN1TSHRGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4014824-A | HYDANTOIN DERIVATIVES, EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-4014824-A | HYDANTOIN DERIVATIVES, EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1977-03-29 | — | — | US | disclosed |
| US-3925407-A | Triglycidyl compounds and their use | CIBA GEIGY CORP | 1975-12-09 | — | — | US | disclosed |