SCHEMBL8991932

SCHEMBL8991932

O=C1CC(=O)N(CC(O)CO)C(=O)N1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 11/20 0.40
KMT2A Q03164 11/20 0.40
MAPT P10636 8/20 0.40
ALDH1A1 P00352 4/20 0.40
HSD17B10 Q99714 3/20 0.40
POLB P06746 3/20 0.40
APEX1 P27695 2/20 0.40
RECQL P46063 2/20 0.40
TDP1 Q9NUW8 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2C9 P11712 1/20 0.40
PKM P14618 1/20 0.40
CYP2C19 P33261 1/20 0.40
PSMD14 O00487 1/20 0.40
MMP2 P08253 1/20 0.40
DNMT1 P26358 1/20 0.40
PTPN7 P35236 1/20 0.40
HBB P68871 1/20 0.40
KDM4C Q9H3R0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14185382 0.77 MEN1 (0.46) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL2376601 0.76 MAPT (0.45) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL11684286 0.74 ABL1 (0.55) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL8415311 0.73 MAPT (0.51) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL8461039 0.72 MEN1 (0.51) MEN1KMT2AMAPTALDH1A1POLB
SCHEMBL9082004 0.70 ALDH1A1 (0.49) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL112155 0.70 MAPT (0.36) MAPTALDH1A1TDP1ATMLMNA
SCHEMBL9083880 0.69 MAPT (0.47) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL9178083 0.69 MEN1 (0.43) MEN1KMT2AMAPTALDH1A1HSD17B10
SCHEMBL145904 0.69 MAPT (0.49) MEN1KMT2AMAPTALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113382719-A Compositions for delivery of therapeutic agents, methods of use and methods of preparation thereof 迪斯拉普申实验室公司 2021-09-10 CN disclosed
EP-0719304-A1 PROCESS FOR THE PRODUCTION OF CYANINE DYES AGFA-GEVAERT N.V. (BE) 1996-07-03 EP disclosed
WO-1995007950-A1 PROCESS FOR THE PRODUCTION OF CYANINE DYES AGFA-GEVAERT NAAMLOZE VENNOOTSCHAP (BE) 1995-03-23 WO disclosed