Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.56 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4099919 | 0.87 | ALDH1A1 (0.69) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL11684411 | 0.86 | ALDH1A1 (0.68) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL2747530 | 0.84 | ALDH1A1 (0.60) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL30445111 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL7566531 | 0.81 | ALDH1A1 (0.65) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL2156946 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL3824914 | 0.81 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL8632332 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL17204612 | 0.80 | ALDH1A1 (0.63) | ALDH1A1TDP1CYP3A4TSHRKMT2A | |
| SCHEMBL4337680 | 0.79 | ALDH1A1 (0.62) | ALDH1A1TDP1CYP3A4TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4016282-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-04-05 | — | — | US | disclosed |
| US-3980792-A | EFFECTIVE AGAINST GRAM-NEGATIVE AND GRAM-POSITIVE INFECTIONS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-09-14 | — | — | US | disclosed |
| US-3978223-A | UREIDOACETAMIDO-PENICILLINS FOR TREATING BACTERIAL INFECTIONS | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-31 | — | — | US | disclosed |
| US-3974140-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-08-10 | — | — | US | disclosed |
| US-3959258-A | BACTERICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |
| US-3939149-A | BACTERICIDE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-17 | — | — | US | disclosed |
| US-3936442-A | ANTIBIOTIC | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | disclosed |
| US-3933795-A | Ureidoacetamido-penicillins | Konig, Hans-Bodo (DT) | 1976-01-20 | — | — | US | disclosed |