Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 4/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | RAF1 | P04049 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.60 |
| ▸ | GFER | P55789 | 1/20 | 0.60 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4818648 | 0.95 | CYP3A4 (0.69) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL10585792 | 0.92 | ALDH1A1 (0.67) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL7787627 | 0.91 | TTR (0.58) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL4818681 | 0.91 | ALDH1A1 (0.59) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL4818707 | 0.91 | TUBB4A (0.62) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL2156946 | 0.90 | ALDH1A1 (0.63) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL176357 | 0.88 | TTR (0.68) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL30825381 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL4337680 | 0.88 | ALDH1A1 (0.62) | ALDH1A1CYP3A4TSHRTDP1KMT2A | |
| SCHEMBL8406656 | 0.87 | ALDH1A1 (0.55) | ALDH1A1CYP3A4TSHRTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112321440-B | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-09-24 | — | — | CN | disclosed |
| CN-112321440-A | Amino phenyl ketone compound and preparation method and application thereof | 南方医科大学 | 2021-02-05 | — | — | CN | disclosed |
| US-9206125-B2 | Use of compound binding to mSin3B that specifically binds to neuron restrictive silencer factor (NRSF) | PUBLIC UNIVERSITY CORPORATION YOKOHAMA CITY UNIVERSITY (JP) | 2015-12-08 | — | — | US | disclosed |
| EP-2098226-A1 | AKAP-PKA interaction inhibitors for use in the treatment of heart diseases | Forschungsverbund Berlin e.V. (DE) | 2009-09-09 | — | — | EP | disclosed |
| CN-1287117-A | Cyclobutene derivatives, preparation method and therapeutic use thereof | SANKYO CO (JP) | 2001-03-14 | — | — | CN | disclosed |
| US-5710334-A | PENDANT ETHER GROUPS, POLYIMIDES WITH IMPROVED SOLUBILITY, MELT FLOW STABILITY, PROCESSABILITY | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-01-20 | — | — | US | disclosed |
| EP-0572196-B1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS (JP) | 1997-08-06 | — | — | EP | disclosed |
| US-5480965-A | BASED ON A NOVEL DIAMINO COMPOUND DERIVED FROM BENZOPHENONE STRUCTURE; FIBER REINFORCEMENT | MITSUI TOATSU CHEMICALS, INC. (JP) | 1996-01-02 | — | — | US | disclosed |
| EP-0572196-A1 | Polyimide, and preparation process of same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1993-12-01 | — | — | EP | disclosed |