SCHEMBL11243895

SCHEMBL11243895

Nc1ccc(S(=O)(=O)O)cc1C(F)(F)F

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 11/20 0.54
ALDH1A1 P00352 5/20 0.52
HSD17B10 Q99714 3/20 0.52
FFAR1 O14842 3/20 0.50
CYP2C9 P11712 1/20 0.46
CYP2C19 P33261 1/20 0.46
CASP6 P55212 1/20 0.46
TSHR P16473 2/20 0.45
NT5E P21589 2/20 0.45
TDP1 Q9NUW8 1/20 0.44
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
GAA P10253 1/20 0.43
MAPT P10636 1/20 0.43
PKM P14618 1/20 0.43
RAB9A P51151 1/20 0.43
KMT2A Q03164 1/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11516738 0.85 ALDH1A1 (0.56) FFAR4ALDH1A1HSD17B10FFAR1CYP2C9
SCHEMBL2810971 0.85 FFAR4 (0.54) FFAR4ALDH1A1FFAR1CYP2C9TSHR
SCHEMBL11682704 0.83 FFAR4 (0.67) FFAR4FFAR1TSHRMEN1MAPT
SCHEMBL11685070 0.83 CA12 (0.58) FFAR4FFAR1KDM4EMEN1GAA
SCHEMBL370204 0.82 ALDH1A1 (0.42) FFAR4ALDH1A1HSD17B10CYP2C9CYP2C19
Methane SCHEMBL11684647 0.82 FFAR4 (0.66) FFAR4FFAR1TSHRMEN1MAPT
SCHEMBL11518943 0.82 FFAR4 (0.64) FFAR4FFAR1TSHRMEN1GAA
SCHEMBL6514474 0.81 FFAR4 (0.54) FFAR4ALDH1A1FFAR1
SCHEMBL11684501 0.81 FFAR4 (0.54) FFAR4FFAR1TSHRMEN1KMT2A
Methane SCHEMBL11683666 0.81 FFAR4 (0.63) FFAR4FFAR1TSHRGAACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4340430-A Azo pigments, process for their production and their use CIBA-GEIGY CORPORATION (US) 1982-07-20 US disclosed
EP-0024261-A1 Azo pigments and process for their preparation, and their use CIBA-GEIGY AG (CH) 1981-02-25 EP disclosed
US-4055557-A MONOAZO DYES BAYER AKTIENGESELLSCHAFT (DT) 1977-10-25 US disclosed