Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682723 | 0.90 | CNR2 (0.42) | KMT2AMEN1TDP1DRD2DRD3 | |
| SCHEMBL11684276 | 0.90 | MAPT (0.43) | KMT2AMEN1TDP1DRD2DRD3 | |
| SCHEMBL11685305 | 0.89 | KMT2A (0.42) | KMT2AMEN1TDP1DRD2DRD3 | |
| SCHEMBL11681966 | 0.87 | KMT2A (0.47) | KMT2AMEN1TDP1HPGDSMN1; SMN2 | |
| SCHEMBL11681443 | 0.85 | KMT2A (0.39) | KMT2AMEN1TDP1DRD2DRD3 | |
| SCHEMBL11682360 | 0.84 | CNR2 (0.45) | KMT2AMEN1TDP1CNR2HPGD | |
| SCHEMBL11683398 | 0.83 | LMNA (0.43) | KMT2AMEN1THRBSMN1; SMN2ALDH1A1 | |
| SCHEMBL8517200 | 0.82 | CNR2 (0.50) | KMT2AMEN1TDP1CNR2CNR1 | |
| SCHEMBL29429236 | 0.82 | CNR2 (0.50) | KMT2AMEN1TDP1CNR2CNR1 | |
| SCHEMBL29231144 | 0.81 | CNR2 (0.55) | KMT2AMEN1TDP1CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4041024-A | FOR POLYAMIDES AND POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-09 | — | — | US | disclosed |