Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 4/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28251651 | 0.85 | PTGS2 (0.52) | PTGS2MAPTAPPGAAAKR1C3 | |
| SCHEMBL4032454 | 0.84 | PTGS2 (0.56) | PTGS2MAPTAPPAKR1C3NQO2 | |
| SCHEMBL4032452 | 0.84 | PTGS2 (0.56) | PTGS2MAPTAPPAKR1C3NQO2 | |
| SCHEMBL22231419 | 0.79 | PTGS2 (0.49) | PTGS2MAPT | |
| SCHEMBL27512287 | 0.78 | DHODH (0.50) | PTGS2MAPTAPPAKR1C3NQO2 | |
| SCHEMBL27536182 | 0.78 | DHODH (0.50) | PTGS2MAPTAPPAKR1C3NQO2 | |
| SCHEMBL22231429 | 0.76 | AKR1C3 (0.48) | PTGS2MAPTCNR2APPGAA | |
| SCHEMBL22231431 | 0.76 | AKR1C3 (0.48) | PTGS2MAPTCNR2APPGAA | |
| SCHEMBL29188761 | 0.74 | DHODH (0.46) | PTGS2MAPTAPPAKR1C3NQO2 | |
| SCHEMBL6791067 | 0.74 | APP (0.45) | PTGS2MAPTAPPAKR1C3NQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053415-A | UNSATURATED POLYESTER ETHER HAVING A PHOTOCROSSLINKABLE MOIETY | FUJI PHOTO FILM CO., LTD. (JA) | 1977-10-11 | — | — | US | disclosed |