Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.52 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.49 |
| ▸ | MMP2 | P08253 | 1/20 | 0.49 |
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MMP8 | P22894 | 1/20 | 0.49 |
| ▸ | MMP13 | P45452 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11682942 | 0.91 | MAPT (0.52) | MAPTKEAP1NFE2L2CA1CA2 | |
| SCHEMBL14988893 | 0.85 | MAPT (0.54) | MAPTCA1CA2MMP1MMP2 | |
| SCHEMBL30556228 | 0.85 | MAPT (0.54) | MAPTCA1CA2MMP1MMP2 | |
| SCHEMBL155420 | 0.85 | MAPT (0.54) | MAPTCA1CA2MMP1MMP2 | |
| SCHEMBL11682721 | 0.85 | MAPT (0.76) | MAPTCA1CA2MMP1MMP2 | |
| SCHEMBL14988889 | 0.84 | MAPT (0.52) | MAPTCA1CA2MMP1MMP2 | |
| SCHEMBL11684031 | 0.83 | MAPT (0.62) | MAPTCA1CA2LMNAALDH1A1 | |
| SCHEMBL11682532 | 0.78 | ACLY (0.47) | MAPTLMNAALDH1A1MEN1KMT2A | |
| SCHEMBL11686358 | 0.77 | FFAR4 (0.54) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL11685580 | 0.77 | LMNA (0.54) | LMNAALDH1A1MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4055557-A | MONOAZO DYES | BAYER AKTIENGESELLSCHAFT (DT) | 1977-10-25 | — | — | US | disclosed |