Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAOB | P27338 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 2/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.43 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796911 | 0.92 | MIF (0.50) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11796905 | 0.86 | NPC1 (0.46) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11686369 | 0.84 | NPC1 (0.51) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL11686365 | 0.82 | NPC1 (0.49) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL12304251 | 0.75 | NPC1 (0.54) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL5708104 | 0.74 | NPC1 (0.57) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL9767790 | 0.73 | NPC1 (0.56) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL17279823 | 0.72 | KDM4E (0.56) | NPC1RAB9AKDM4EALDH1A1KMT2A | |
| SCHEMBL3377170 | 0.70 | MIF (0.58) | MIFNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL2633294 | 0.70 | NPC1 (0.58) | MIFNPC1RAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008248-A | OPTICAL BRIGTENER | BAYER AKTIENGESELLSCHAFT (DT) | 1977-02-15 | — | — | US | disclosed |