SCHEMBL2633294

SCHEMBL2633294

Cc1nc(C)nc(-c2ccc3cc(-c4ccccc4)c(=O)oc3c2)n1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 8/20 0.58
MIF P14174 4/20 0.58
RAB9A P51151 7/20 0.58
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 4/20 0.57
MAOB P27338 2/20 0.57
KMT2A Q03164 2/20 0.53
GLA P06280 2/20 0.53
MEN1 O00255 1/20 0.53
ESR2 Q92731 2/20 0.50
HPGD P15428 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.49
GAA P10253 2/20 0.49
NCOA1 Q15788 1/20 0.49
NCOA3 Q9Y6Q9 1/20 0.49
ESR1 P03372 1/20 0.49
GAPDH P04406 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
KLK7 P49862 1/20 0.48
HSD11B1 P28845 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12304339 0.83 MAOB (0.77) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL3277676 0.81 NPC1 (0.58) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL27125498 0.77 NPC1 (0.56) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL10024076 0.76 MIF (0.77) MIFRAB9AKDM4EALDH1A1MAOB
SCHEMBL177366 0.74 RAB9A (1.00) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL30356319 0.74 RAB9A (1.00) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL12304253 0.74 MIF (0.59) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL984946 0.74 NPC1 (0.77) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL5008342 0.74 NPC1 (0.68) NPC1MIFRAB9AKDM4EALDH1A1
SCHEMBL9368300 0.74 NPC1 (0.68) NPC1MIFRAB9AKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1983378-B1 Magenta toner for developing electrostatic image KONICA MINOLTA BUSINESS TECH (JP) 2012-04-25 EP disclosed
US-8062819-B2 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-11-22 US disclosed
US-8062819-B2 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2011-11-22 US disclosed
US-20080261141-A1 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-23 US disclosed
US-20080261141-A1 tone controlling agent having a peak of fluorescent spectrum within the range of from 380 to 500 nm; light fastness and durability and high color reproducibility with sufficient transparency, chromaticness KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-23 US disclosed
EP-1983378-A2 Magenta toner for developing electrostatic image KONICA MINOLTA BUSINESS TECHNOLOGIES, INC. (JP) 2008-10-22 EP disclosed