Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | MIF | P14174 | 5/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.48 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3377170 | 0.79 | MIF (0.58) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL5921545 | 0.78 | GPR35 (0.56) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL27125498 | 0.78 | NPC1 (0.56) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11881599 | 0.76 | CYP19A1 (0.54) | KDM4EALDH1A1KMT2AMEN1GLA | |
| SCHEMBL12304251 | 0.76 | NPC1 (0.54) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11686365 | 0.74 | NPC1 (0.49) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL3277676 | 0.74 | NPC1 (0.58) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL2633294 | 0.74 | NPC1 (0.58) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11686369 | 0.73 | NPC1 (0.51) | NPC1MIFRAB9AKDM4EALDH1A1 | |
| SCHEMBL11685698 | 0.73 | MIF (0.51) | NPC1MIFRAB9AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0030917-B2 | OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1991-03-20 | — | — | EP | disclosed |
| US-5001253-A | Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1991-03-19 | — | — | US | disclosed |
| US-4785128-A | Process for the preparation of bis-styrylbenzenes | CIBA-GEIGY CORPORATION (US) | 1988-11-15 | — | — | US | disclosed |
| US-4778623-A | Fluorescent brighteners consisting of bis-styrylbenzene compounds, a process for their preparation and their use | CIBA-GEIGY CORPORATION (US) | 1988-10-18 | — | — | US | disclosed |
| EP-0030917-B1 | OPTICAL BRIGHTENERS FROM BISTYRYL BENZENE, PROCESS FOR THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1985-01-23 | — | — | EP | disclosed |
| EP-0030917-A2 | Optical brighteners from bistyryl benzene, process for their preparation and their use | CIBA-GEIGY AG (CH) | 1981-06-24 | — | — | EP | disclosed |