SCHEMBL11686016

SCHEMBL11686016

CC(=O)NC(C)(C(=O)S)C(C)C

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.32
EPHX1 P07099 1/20 0.31
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9159698 0.79 ALDH1A1 (0.33) PIK3CDEPHX1POLB
SCHEMBL9333241 0.77 CNR2 (0.33) PIK3CDEPHX1POLB
SCHEMBL11683699 0.76 EPHX1 (0.39) PIK3CDEPHX1
SCHEMBL11686026 0.76 EPHX1 (0.39) PIK3CDEPHX1
SCHEMBL7300432 0.74 ALDH1A1 (0.31) PIK3CD
SCHEMBL12267723 0.70 PIK3CD (0.37) PIK3CDEPHX1POLB
SCHEMBL11683952 0.70 EPHX1 (0.36) EPHX1
SCHEMBL8435450 0.70 PIK3CD (0.52) PIK3CDEPHX1POLB
SCHEMBL10363713 0.69 EPHX1 (0.34) EPHX1
SCHEMBL4121532 0.68 TP53 (0.32) EPHX1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002682-A CHEMICAL INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1977-01-11 US disclosed
US-3952044-A INTERMEDIATES SAGAMI CHEMICAL RESEARCH CENTER (JA) 1976-04-20 US disclosed