SCHEMBL9159698

SCHEMBL9159698

CC(=O)NC(C)(C(=O)O)C(C)C

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.33
TSHR P16473 1/20 0.33
PIK3CD O00329 1/20 0.33
EPHX1 P07099 1/20 0.32
POLB P06746 1/20 0.31
MAPK1 P28482 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4121532 0.84 TP53 (0.32) ALDH1A1TSHREPHX1POLB
SCHEMBL11683699 0.82 EPHX1 (0.39) ALDH1A1PIK3CDEPHX1
SCHEMBL11686026 0.82 EPHX1 (0.39) ALDH1A1PIK3CDEPHX1
SCHEMBL11686016 0.79 PIK3CD (0.32) PIK3CDEPHX1POLB
SCHEMBL9333241 0.79 CNR2 (0.33) ALDH1A1PIK3CDEPHX1POLB
SCHEMBL12175227 0.77 CA12 (0.33) ALDH1A1TSHRPIK3CD
SCHEMBL19578354 0.77 CA12 (0.33) ALDH1A1TSHRPIK3CD
SCHEMBL24965898 0.76 CA2 (0.36) ALDH1A1PIK3CDPOLB
SCHEMBL3528813 0.76 CA1 (0.42)
SCHEMBL3528810 0.76 CA1 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0353248-B1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR INC (US) 1995-03-29 EP disclosed
US-5391757-A Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1995-02-21 US disclosed
US-5338883-A Benzenesulfonyl carboxamide compounds intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1994-08-16 US disclosed
US-5252539-A Benzenesulfonyl carboxamide compounds intermediate compounds and method of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1993-10-12 US disclosed
US-5120854-A Benzenesulfonyl carboxamide compounds and intermediate compounds AMERICAN CYANAMID COMPANY (US) 1992-06-09 US disclosed
EP-0353248-A4 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS 1991-07-17 EP disclosed
US-4992094-A Herbicides AMERICAN CYANAMID COMPANY (US) 1991-02-12 US disclosed
EP-0353248-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS. SEPRACOR INC (US) 1990-02-07 EP disclosed
US-4883914-A Benzenesulfonyl carboxamide compounds useful as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1989-11-28 US disclosed
EP-0303863-A2 Benzenesulfonyl carboxamide compounds, intermediate compounds and methods of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1989-02-22 EP disclosed
US-4800162-A ENZYME-ACTIVATED MEMBRANE SEPRACOR, INC. (US) 1989-01-24 US disclosed
WO-1988007582-A1 METHOD FOR RESOLUTION OF STEREOISOMERS IN MULTIPHASE AND EXTRACTIVE MEMBRANE REACTORS SEPRACOR, INC. (US) 1988-10-06 WO disclosed
US-4125727-A Method of preparing imidazoisoindolediones AMERICAN CYANAMID COMPANY (US) 1978-11-14 US disclosed
US-4062671-A Imidazoisoindolediones, and the use thereof as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1977-12-13 US disclosed
US-4017510-A ENANTIOMORPHS AMERICAN CYANAMID COMPANY (US) 1977-04-12 US disclosed