Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.67 |
| ▸ | MAPT | P10636 | 6/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.67 |
| ▸ | DRD3 | P35462 | 5/20 | 0.67 |
| ▸ | DRD2 | P14416 | 5/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.67 |
| ▸ | HTR1A | P08908 | 5/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 4/20 | 0.67 |
| ▸ | HTR2A | P28223 | 4/20 | 0.67 |
| ▸ | HTR2C | P28335 | 4/20 | 0.67 |
| ▸ | HRH1 | P35367 | 4/20 | 0.67 |
| ▸ | HTR2B | P41595 | 4/20 | 0.67 |
| ▸ | TP53 | P04637 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686598 | 0.91 | KDM1A (0.67) | LMNAMAPK1CYP2D6ADRA2ASLC6A2 | |
| Hydrochloric Acid SCHEMBL11688568 | 0.90 | KDM1A (0.66) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| SCHEMBL11686349 | 0.87 | CYP2D6 (0.51) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| SCHEMBL11688782 | 0.87 | KDM1A (0.62) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL11688567 | 0.87 | CYP2D6 (0.50) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| SCHEMBL11684752 | 0.87 | KDM1A (0.61) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| SCHEMBL11687350 | 0.86 | FPR2 (0.74) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL11690802 | 0.86 | KDM1A (0.60) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| Hydrochloric Acid SCHEMBL11686712 | 0.85 | FPR2 (0.73) | LMNAMAPK1MAPTCYP2D6ADRA2A | |
| SCHEMBL11686342 | 0.84 | CYP2D6 (0.72) | LMNAMAPK1MAPTCYP2D6ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018922-A | NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES | ROUSSEL-UCLAF (FR) | 1977-04-19 | — | — | US | disclosed |