Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.72 |
| ▸ | LMNA | P02545 | 7/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.72 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.72 |
| ▸ | DRD3 | P35462 | 6/20 | 0.72 |
| ▸ | MAPT | P10636 | 6/20 | 0.72 |
| ▸ | DRD2 | P14416 | 5/20 | 0.72 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.72 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.72 |
| ▸ | HTR2A | P28223 | 5/20 | 0.72 |
| ▸ | HTR2C | P28335 | 5/20 | 0.72 |
| ▸ | HRH1 | P35367 | 5/20 | 0.72 |
| ▸ | HTR2B | P41595 | 5/20 | 0.72 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.72 |
| ▸ | TP53 | P04637 | 5/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.72 |
| ▸ | HTR1A | P08908 | 5/20 | 0.72 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11690756 | 0.99 | LMNA (0.71) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| SCHEMBL11686604 | 0.91 | KDM1A (0.64) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11688573 | 0.90 | KDM1A (0.62) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| SCHEMBL11688791 | 0.87 | KDM1A (0.58) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| Flupimazine SCHEMBL2109271 | 0.86 | FPR2 (0.75) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| SCHEMBL11684759 | 0.86 | KDM1A (0.57) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| Flupimazine SCHEMBL11684459 | 0.85 | LMNA (0.74) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL11690805 | 0.85 | KDM1A (0.56) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| SCHEMBL11686337 | 0.84 | LMNA (0.67) | CYP2D6MAPK1LMNASLC6A2SLC6A4 | |
| Perphenazine SCHEMBL42125 | 0.84 | MAPT (1.00) | CYP2D6MAPK1LMNASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018922-A | NEUROLEPTICS, ANALGESICS, SPASMOLYTICS, AND ANTIHISTAMINES | ROUSSEL-UCLAF (FR) | 1977-04-19 | — | — | US | disclosed |