Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 2/20 | 0.40 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | MMP12 | P39900 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18724536 | 0.78 | SIRT2 (0.45) | MAPK1SMN1; SMN2HSD17B10L3MBTL1DDB1 | |
| SCHEMBL10821188 | 0.77 | MAOB (0.52) | GSK3BMAOAMAOBALDH1A1 | |
| SCHEMBL10019245 | 0.75 | MAPK1 (0.41) | MAPK1SMN1; SMN2HSD17B10L3MBTL1DDB1 | |
| SCHEMBL10019244 | 0.75 | MAPK1 (0.44) | MAPK1SMN1; SMN2HSD17B10L3MBTL1DDB1 | |
| SCHEMBL1818465 | 0.75 | CLK4 (0.46) | MAPK1SMN1; SMN2HSD17B10L3MBTL1DDB1 | |
| SCHEMBL10704412 | 0.74 | MAOA (0.56) | MAPK1SMN1; SMN2HSD17B10L3MBTL1DDB1 | |
| SCHEMBL10821046 | 0.74 | MAOA (0.50) | MAPK1DDB1CRBNMAOAMAOB | |
| SCHEMBL2952763 | 0.74 | GRM5 (0.50) | MAPK1L3MBTL1DDB1CRBNMAOA | |
| SCHEMBL11687141 | 0.74 | APEX1 (0.33) | — | |
| SCHEMBL10777512 | 0.74 | ACHE (0.41) | SMN1; SMN2L3MBTL1DDB1CRBNMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045435-A | Preparation of cephalosporin ethers | ELI LILLY AND COMPANY (US) | 1977-08-30 | — | — | US | disclosed |
| US-3953438-A | Preparation of cephalosporin ethers | ELI LILLY AND COMPANY (US) | 1976-04-27 | — | — | US | disclosed |