Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11686489 | 0.81 | TDP1 (0.43) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL4186050 | 0.81 | BCHE (0.44) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL27740561 | 0.79 | NPC1 (0.42) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL107013 | 0.77 | CNR2 (0.49) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL2589900 | 0.77 | MEN1 (0.51) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL157807 | 0.77 | MEN1 (0.51) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL1685257 | 0.77 | TSHR (0.46) | TDP1ESR1MEN1KMT2ANPSR1 | |
| SCHEMBL18074044 | 0.76 | CNR2 (0.48) | TDP1ESR1MEN1KMT2ANPSR1 | |
| Bromide SCHEMBL10687133 | 0.76 | MEN1 (0.50) | TDP1ESR1MEN1KMT2ANPSR1 | |
| Hydrochloric Acid SCHEMBL2141325 | 0.76 | CNR2 (0.48) | TDP1ESR1MEN1KMT2ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4008999-A | N,N-dialkylamino diphenylamines for dyeing keratinic fibers | SOCIETE ANONYME DITE: L'OREAL (FR) | 1977-02-22 | — | — | US | disclosed |