SCHEMBL1685257

SCHEMBL1685257

CCN(CC)N(c1ccccc1)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
ALDH1A1 P00352 2/20 0.46
GLA P06280 1/20 0.46
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
CHRM1 P11229 1/20 0.40
DRD1 P21728 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40
ADRA1A P35348 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
SLC6A3 Q01959 1/20 0.40
KCNH2 Q12809 1/20 0.40
KMT2A Q03164 4/20 0.38
MEN1 O00255 3/20 0.38
TP53 P04637 2/20 0.38
CNR2 P34972 1/20 0.38
MAPT P10636 3/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6711036 0.87 TSHR (0.38) TSHRALDH1A1GLACHRM2HTR1A
SCHEMBL27774101 0.87 ALDH1A1 (0.59) TSHRALDH1A1GLAKMT2AMEN1
Benzophenone SCHEMBL9593853 0.84 ALDH1A1 (0.56) TSHRALDH1A1GLAADRA2AKCNH2
SCHEMBL9437404 0.82 ALDH1A1 (0.47) TSHRALDH1A1GLAKMT2AMEN1
Hydrochloric Acid SCHEMBL11760197 0.77 TSHR (0.45) TSHRALDH1A1GLACHRM2HTR1A
SCHEMBL3572173 0.77 TSHR (0.45) TSHRALDH1A1GLACHRM2HTR1A
SCHEMBL4205031 0.77 TSHR (0.45) TSHRALDH1A1GLACHRM2HTR1A
SCHEMBL11686709 0.77 TDP1 (0.44) ALDH1A1CHRM2HTR1AADRA2ACHRM1
SCHEMBL28159760 0.75 TSHR (0.43) TSHRALDH1A1GLACHRM2HTR1A
SCHEMBL27857943 0.75 ALDH1A1 (0.48) TSHRALDH1A1GLACHRM2HTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8562812-B2 Sulphuration method of ferrous alloy parts in an aqueous solution H.E.F. (FR) 2013-10-22 US claimed
EP-1379565-B1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2011-04-06 EP claimed
US-7592386-B2 Dual cure hydrotalcite containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-22 US claimed
EP-2084224-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-08-05 EP claimed
WO-2008063905-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-29 WO claimed
US-20080116603-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-05-22 US claimed
EP-1551915-B1 FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES CO (US) 2007-09-12 EP claimed
US-7592386-B2 Dual cure hydrotalcite containing fluoropolymer compositions 3M INNOVATIVE PROPERTIES COMPANY (US) 2009-09-22 US disclosed
EP-2084224-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M Innovative Properties Company (US) 2009-08-05 EP disclosed
WO-2008063905-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY (US) 2008-05-29 WO disclosed
US-20080116603-A1 DUAL CURE HYDROTALCITE CONTAINING FLUOROPOLYMER COMPOSITIONS 3M INNOVATIVE PROPERTIES COMPANY 2008-05-22 US disclosed
US-4008999-A N,N-dialkylamino diphenylamines for dyeing keratinic fibers SOCIETE ANONYME DITE: L'OREAL (FR) 1977-02-22 US disclosed