Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | DHFR | P00374 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL157807 | 1.00 | MEN1 (0.51) | MEN1KMT2ACASP1BRCA1CASP7 | |
| Bromide SCHEMBL10687133 | 0.98 | MEN1 (0.50) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL720769 | 0.93 | NPC1 (0.50) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL4367549 | 0.92 | MEN1 (0.47) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL2849795 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL1204768 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL60682 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL7924615 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL985190 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 | |
| SCHEMBL619876 | 0.91 | NPC1 (0.53) | MEN1KMT2ACASP1BRCA1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729467-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2014-05-14 | — | — | EP | disclosed |
| EP-2564446-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | Commonwealth Scientific and Industrial Research Organisation (AU) | 2013-03-06 | — | — | EP | disclosed |
| WO-2013003912-A1 | CRYPTATE COMPOUNDS | AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION (AU) | 2013-01-10 | — | — | WO | disclosed |
| WO-2011134013-A1 | ELECTROLUMINESCENT DEVICES BASED ON PHOSPHORESCENT IRIDIUM AND RELATED GROUP VIII METAL MULTICYCLIC COMPOUNDS | COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) | 2011-11-03 | — | — | WO | disclosed |