Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.46 |
| ▸ | MAPT | P10636 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11672541 | 0.91 | PLCG1 (0.63) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11672539 | 0.91 | PLCG1 (0.63) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11101773 | 0.88 | PLCG1 (0.66) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11672615 | 0.88 | PLCG1 (0.79) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11305923 | 0.88 | PLCG1 (0.66) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11672611 | 0.88 | PLCG1 (0.79) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11040053 | 0.88 | PLCG1 (0.79) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11040054 | 0.88 | PLCG1 (0.79) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11673831 | 0.88 | PLCG1 (0.65) | PLCG1CTDSP1TDP1MAPTCYP3A4 | |
| SCHEMBL11673833 | 0.88 | PLCG1 (0.65) | PLCG1CTDSP1TDP1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4042585-A | Process for preparation of 3-halomethylcephems | ELI LILLY AND COMPANY (US) | 1977-08-16 | — | — | US | disclosed |