SCHEMBL11688232

SCHEMBL11688232

CC(C)CN=NCC(C)O

nearest known ligand 0.37

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.37
TDP1 Q9NUW8 1/20 0.37
ALDH1A1 P00352 1/20 0.35
TRPA1 O75762 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9190329 0.90 TSHR (0.44) TSHRTDP1ALDH1A1
SCHEMBL1487502 0.83 TRPA1 (0.42) TSHRTRPA1
SCHEMBL166950 0.83 TRPA1 (0.42) TSHRTRPA1
SCHEMBL11586128 0.78 TSHR (0.32) TSHRTDP1
SCHEMBL17425741 0.73
SCHEMBL19673514 0.73
SCHEMBL19673174 0.73
SCHEMBL11071930 0.71
SCHEMBL1536086 0.69
SCHEMBL23541947 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029615-A AZO COMPOUNDS PENNWALT CORPORATION (US) 1977-06-14 US disclosed
US-3993609-A ACID SENSITIVE AZO PROMOTERS PENNWALT CORPORATION (US) 1976-11-23 US disclosed