SCHEMBL11689596

SCHEMBL11689596

CCN(CC)S(=O)(=O)c1cc(Cl)c(N)c(Cl)c1

nearest known ligand 0.58

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.58
NPSR1 Q6W5P4 2/20 0.58
MAPT P10636 2/20 0.53
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
VCAM1 P19320 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
LMNA P02545 2/20 0.48
HTT P42858 2/20 0.48
TSHR P16473 2/20 0.47
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
POLB P06746 1/20 0.44
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11688729 0.90 ALDH1A1 (0.53) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL11689696 0.89 CA1 (0.60) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL11684860 0.87 ALDH1A1 (0.47) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL11650278 0.81 ALDH1A1 (0.58) ALDH1A1NPSR1MAPTVCAM1SMN1; SMN2
SCHEMBL10693591 0.81 ALDH1A1 (0.60) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL11687653 0.79 VCAM1 (0.52) ALDH1A1NPSR1MAPTCA1CA2
SCHEMBL11444393 0.79 CA1 (0.57) ALDH1A1CA1CA2CA9VCAM1
SCHEMBL197477 0.79 ALDH1A1 (0.54) ALDH1A1NPSR1MAPTVCAM1SMN1; SMN2
SCHEMBL10695843 0.78 TSHR (0.54) ALDH1A1NPSR1CA1CA2CA9
SCHEMBL5461567 0.77 ALDH1A1 (0.65) ALDH1A1NPSR1MAPTVCAM1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4026931-A AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT BAYER AKTIENGESELLSCHAFT (DT) 1977-05-31 US disclosed