Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.64 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28113183 | 0.81 | KEAP1 (0.62) | LMNASLC12A2SLC12A5KEAP1POLB | |
| SCHEMBL120482 | 0.79 | LMNA (0.69) | LMNASLC12A2SLC12A5KEAP1GLA | |
| SCHEMBL10904363 | 0.79 | LMNA (0.69) | LMNASLC12A2SLC12A5KEAP1GLA | |
| SCHEMBL407414 | 0.77 | KEAP1 (1.00) | LMNASLC12A2SLC12A5KEAP1POLB | |
| SCHEMBL8789480 | 0.77 | CYP19A1 (0.78) | LMNASLC12A2SLC12A5KEAP1GLA | |
| SCHEMBL151655 | 0.77 | KEAP1 (0.76) | LMNASLC12A2SLC12A5KEAP1POLB | |
| SCHEMBL31339948 | 0.76 | CYP19A1 (0.85) | LMNASLC12A2SLC12A5KEAP1POLB | |
| SCHEMBL5952598 | 0.76 | KEAP1 (0.64) | LMNASLC12A2SLC12A5KEAP1GLA | |
| SCHEMBL5032445 | 0.76 | CYP19A1 (0.85) | LMNASLC12A2SLC12A5KEAP1POLB | |
| SCHEMBL27670793 | 0.76 | KEAP1 (0.69) | LMNASLC12A2SLC12A5KEAP1VCAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106146358-B | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2018-01-23 | — | — | CN | disclosed |
| CN-106146358-A | Method for synthesizing amino- (N-alkyl) benzene sulfonamide | 南京理工大学 | 2016-11-23 | — | — | CN | disclosed |
| US-4026931-A | AZO DYES, FIBER-REACTIVE; INDOLE OR 5-AMINO-PYRAZOLE COUPLING COMPONENT | BAYER AKTIENGESELLSCHAFT (DT) | 1977-05-31 | — | — | US | disclosed |