Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.54 |
| ▸ | GSR | P00390 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11694446 | 1.00 | HDAC1 (0.54) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL5426825 | 0.77 | HDAC1 (0.54) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL22596712 | 0.76 | HDAC1 (0.67) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL2744242 | 0.76 | GSR (0.79) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL2744240 | 0.76 | GSR (0.79) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL31553473 | 0.76 | GSR (0.79) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL30468232 | 0.76 | GSR (0.79) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL13729148 | 0.75 | HDAC1 (0.53) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL13729150 | 0.75 | HDAC1 (0.53) | HDAC1HDAC8HDAC6GSRMAPT | |
| SCHEMBL6990827 | 0.75 | MAPT (0.55) | HDAC1HDAC8HDAC6MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061630-A | 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |