SCHEMBL11697017

SCHEMBL11697017

CC(=O)Nc1cc(N(CCOC(C)=O)CCOC(C)=O)ccc1C=O

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MAPT P10636 3/20 0.35
KDM4E B2RXH2 3/20 0.35
SMN1; SMN2 Q16637 3/20 0.35
LMNA P02545 2/20 0.35
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34
SLC16A3 O15427 2/20 0.33
SLC16A1 P53985 2/20 0.33
NPSR1 Q6W5P4 2/20 0.33
PDE3B Q13370 3/20 0.32
PDE3A Q14432 3/20 0.32
P2RY12 Q9H244 3/20 0.32
RAD52 P43351 1/20 0.32
MTNR1A P48039 2/20 0.32
MTNR1B P49286 2/20 0.32
STAT1 P42224 1/20 0.32
RAB9A P51151 1/20 0.32
CYP1A2 P05177 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11844854 0.86 SNCA (0.40) L3MBTL1MAPTKDM4ESMN1; SMN2LMNA
SCHEMBL11699146 0.84 ALDH1A1 (0.35) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL11321969 0.84 MAPT (0.43) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL11695579 0.81 ALDH1A1 (0.52) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL10425633 0.81 ALDH1A1 (0.49) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL21191438 0.78 ALDH1A1 (0.46) ALDH1A1L3MBTL1SMN1; SMN2HPGDSLC16A3
SCHEMBL14940641 0.76 ALDH1A1 (0.47) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL8415573 0.75 ALDH1A1 (0.56) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL11696313 0.75 ALDH1A1 (0.42) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2
SCHEMBL11695763 0.74 ALDH1A1 (0.40) ALDH1A1L3MBTL1MAPTKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4002616-A POLYESTERS E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-01-11 US disclosed
US-3962220-A ONE-STEP, AROMATIC ALDEHYDES, ACETIC ACID E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed
US-3962221-A CONDENSATION, REDUCTION, OXIDATION E. I. DU PONT DE NEMOURS AND COMPANY (US) 1976-06-08 US disclosed