SCHEMBL8415573

SCHEMBL8415573

CCN(CCOC(C)=O)c1ccc(C=O)c(OC(C)=O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.56
L3MBTL1 Q9Y468 2/20 0.56
MAPT P10636 7/20 0.39
KDM4E B2RXH2 5/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
LMNA P02545 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
BACE1 P56817 4/20 0.36
GAA P10253 1/20 0.36
MAOB P27338 2/20 0.36
ATM Q13315 2/20 0.36
USP2 O75604 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C19 P33261 1/20 0.36
ALDH3A1 P30838 1/20 0.36
ALDH1A3 P47895 1/20 0.36
SLC16A3 O15427 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10425633 0.94 ALDH1A1 (0.49) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL9361815 0.88 ALDH1A1 (0.70) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL14940641 0.86 ALDH1A1 (0.47) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL7598406 0.83 ALDH1A1 (0.56) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL21191438 0.82 ALDH1A1 (0.46) ALDH1A1L3MBTL1HPGDMEN1KMT2A
SCHEMBL8415313 0.81 ALDH1A1 (0.54) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL5689109 0.80 ALDH1A1 (0.59) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL11321969 0.79 MAPT (0.43) ALDH1A1L3MBTL1MAPTKDM4EHPGD
SCHEMBL21191517 0.78 BACE1 (0.48) ALDH1A1L3MBTL1MEN1KMT2ASMN1; SMN2
SCHEMBL7863602 0.76 ALDH1A1 (0.65) ALDH1A1L3MBTL1MAPTKDM4EHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0565074-B1 Process for the preparation of binary sensitizing dyes EASTMAN KODAK CO (US) 1999-08-25 EP disclosed
US-5756740-A Process for the preparation of binary sensitizing dyes EASTMAN KODAK COMPANY (US) 1998-05-26 US disclosed
EP-0565074-A2 Process for the preparation of binary sensitizing dyes EASTMAN KODAK COMPANY (US) 1993-10-13 EP disclosed