Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | PGR | P06401 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504463 | 1.00 | CA5A (0.57) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL10863671 | 0.99 | CA5A (0.56) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL10897899 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL8441810 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL4348994 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL8441808 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL16202385 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL11161264 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL11161263 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 | |
| SCHEMBL10897895 | 0.89 | NR1I2 (0.47) | CA5ANR1I2ESR1PGRPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4061630-A | 7-Substituted-ureido-3-carbamoyloxymethyl cephalosporin antibiotics | ELI LILLY AND COMPANY (US) | 1977-12-06 | — | — | US | disclosed |