Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1I2 | O75469 | 3/20 | 0.47 |
| ▸ | ESR1 | P03372 | 1/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.47 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.45 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11504463 | 0.89 | CA5A (0.57) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL11697100 | 0.89 | CA5A (0.57) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL10897899 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL11161263 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL10863671 | 0.88 | CA5A (0.56) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL8441808 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL8441810 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL11161264 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL10897895 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR | |
| SCHEMBL4348994 | 0.88 | NR1I2 (0.47) | NR1I2ESR1PGRPTGS2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020099858-A1 | CEPHALOSPORIN CIPROFLOXACIN HYBRID COMPOUNDS | IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY AND MEDICINE (GB) | 2020-05-22 | — | — | WO | disclosed |
| US-9476087-B2 | Methods and compounds for detecting beta-lactamase activity | NANYANG TECHNOLOGICAL UNIVERSITY (SG) | 2016-10-25 | — | — | US | disclosed |
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | UNIV NANYANG TECH (SG) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140322739-A1 | METHODS AND COMPOUNDS FOR DETECTING BETA-LACTAMASE ACTIVITY | LPO, MPO, GUSB | NR1I2 2684/4885ESR1 1516/4885PGR 3954/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.