SCHEMBL11697235

SCHEMBL11697235

Cc1ccc(N(c2ccccc2)C(C)O)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.44
SLC6A4 P31645 1/20 0.44
CYP2C19 P33261 1/20 0.42
TRPM8 Q7Z2W7 2/20 0.41
LMNA P02545 3/20 0.40
TSHR P16473 2/20 0.40
ALOX12 P18054 1/20 0.40
ACHE P22303 1/20 0.40
ALDH1A1 P00352 3/20 0.39
KDM4E B2RXH2 2/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
ALOX5 P09917 1/20 0.39
KMT2A Q03164 2/20 0.38
NPC1 O15118 1/20 0.38
MAPT P10636 1/20 0.38
HTT P42858 1/20 0.38
RAB9A P51151 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ATM Q13315 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11697906 0.91 ALDH1A1 (0.46) SLC6A2SLC6A4CYP2C19LMNATSHR
SCHEMBL5076555 0.89 ALDH1A1 (0.46) SLC6A2SLC6A4CYP2C19LMNATSHR
SCHEMBL4010297 0.83 CYP2C19 (0.42) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL8749808 0.83 ALDH1A1 (0.47) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL13721622 0.78 ALDH1A1 (0.46) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL13721239 0.78 ALDH1A1 (0.46) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL7937528 0.77 ALOX5 (0.44) CYP2C19TRPM8LMNATSHRALOX12
SCHEMBL24564987 0.75 CYP2C19 (0.43) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL18648063 0.75 ALDH1A1 (0.41) SLC6A2SLC6A4CYP2C19TRPM8LMNA
SCHEMBL15458054 0.73 ALDH1A1 (0.48) CYP2C19TRPM8LMNATSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4063887-A HYDROXYAMINE COMPOUND CELANESE CORPORATION (US) 1977-12-20 US disclosed