SCHEMBL11697304

SCHEMBL11697304

O=C(O)CNC(NCC(=O)O)P(=O)(O)O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
MEN1 O00255 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
BLM P54132 1/20 0.42
KMT2A Q03164 1/20 0.42
FOLH1 Q04609 7/20 0.37
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
NAALAD2 Q9Y3Q0 1/20 0.34
ALDH1A1 P00352 1/20 0.32
MAPT P10636 1/20 0.32
PTGS2 P35354 1/20 0.32
ENO1 P06733 1/20 0.32
LDHA P00338 1/20 0.32
SRR Q9GZT4 1/20 0.32
GGH Q92820 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9060867 0.82 LMNA (0.43) LMNATDP1MEN1HPGDTSHR
SCHEMBL31327367 0.76 FOLH1 (0.39) LMNATDP1MEN1HPGDTSHR
SCHEMBL11411525 0.76 LMNA (0.39) LMNATDP1MEN1HPGDTSHR
SCHEMBL8768497 0.75 MEN1 (0.37) LMNATDP1MEN1HPGDTSHR
SCHEMBL3713672 0.75 FOLH1 (0.42) LMNATDP1MEN1HPGDTSHR
SCHEMBL31315301 0.73 MEN1 (0.44) LMNATDP1MEN1HPGDTSHR
SCHEMBL11862752 0.73 LAP3 (0.37) LMNATDP1MEN1HPGDTSHR
SCHEMBL11597672 0.73 LMNA (0.36) LMNATDP1MEN1HPGDTSHR
SCHEMBL11351769 0.73 LMNA (0.36) LMNATDP1MEN1HPGDTSHR
SCHEMBL1412212 0.73 FOLH1 (0.45) FOLH1CA2CA4NAALAD2GGH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4065491-A Process for the preparation of N-phosphonomethyl-glycine CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) 1977-12-27 US disclosed