Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPA5 | P11021 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5139536 | 0.83 | SMN1; SMN2 (0.59) | LMNARECQLSMN1; SMN2NPSR1HIF1A | |
| SCHEMBL12510578 | 0.81 | HSPA5 (0.50) | HSPA5LMNARECQLSMN1; SMN2NPSR1 | |
| SCHEMBL3812720 | 0.81 | GLRA3 (0.52) | HSPA5LMNARECQLSMN1; SMN2NPSR1 | |
| SCHEMBL8960347 | 0.79 | LMNA (0.50) | HSPA5LMNARECQLSMN1; SMN2NPSR1 | |
| SCHEMBL19289494 | 0.77 | HSP90AA1 (0.37) | HSPA5LMNARECQLALDH1A1MAPT | |
| SCHEMBL11698161 | 0.77 | CYP2C9 (0.57) | HSPA5LMNARECQLSMN1; SMN2NPSR1 | |
| SCHEMBL28404083 | 0.76 | HSPA5 (0.56) | HSPA5LMNARECQLSMN1; SMN2NPSR1 | |
| SCHEMBL9556848 | 0.76 | SERPINE1 (0.50) | HSPA5LMNARECQLCA2CA1 | |
| SCHEMBL7606811 | 0.75 | SMN1; SMN2 (0.46) | LMNARECQLSMN1; SMN2NPSR1CYP2C9 | |
| SCHEMBL45878 | 0.74 | HSPA5 (0.75) | HSPA5LMNARECQLSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4045499-A | ACID CATALYSTS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-08-30 | — | — | US | disclosed |