Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | GLRA3 | O75311 | 1/20 | 0.42 |
| ▸ | GLRB | P48167 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10082434 | 0.87 | LMNA (0.37) | LMNARECQLHSPA5SMN1; SMN2ALOX5 | |
| SCHEMBL47590 | 0.85 | LMNA (0.55) | LMNARECQLSMN1; SMN2GLRA3GLRB | |
| SCHEMBL3812720 | 0.84 | GLRA3 (0.52) | LMNARECQLHSPA5SMN1; SMN2CYP2C9 | |
| SCHEMBL8949330 | 0.83 | TSHR (0.46) | LMNASMN1; SMN2CYP2C9HSP90AA1HSP90AB1 | |
| SCHEMBL45856 | 0.81 | LMNA (0.53) | LMNARECQLSMN1; SMN2HIF1AGLRA3 | |
| SCHEMBL11697398 | 0.79 | HSPA5 (0.49) | LMNARECQLHSPA5SMN1; SMN2CYP2C9 | |
| SCHEMBL9556848 | 0.79 | SERPINE1 (0.50) | LMNARECQLHSPA5CA2CA1 | |
| SCHEMBL30924511 | 0.79 | CYP1A2 (0.55) | LMNARECQLHSPA5SMN1; SMN2CYP2C9 | |
| SCHEMBL14235584 | 0.77 | HSP90AA1 (0.44) | LMNARECQLSMN1; SMN2CYP2C9HSP90AA1 | |
| SCHEMBL28404083 | 0.76 | HSPA5 (0.56) | LMNARECQLHSPA5SMN1; SMN2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8222239-B2 | quaternary ammonium compounds, conjugated to polymers, used as microbiocides | ALLACCEM, INC. (US) | 2012-07-17 | — | — | US | disclosed |
| US-8188068-B2 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | ALLACCEM, INC. (US) | 2012-05-29 | — | — | US | disclosed |
| US-20110015300-A1 | METHODS AND SYSTEMS FOR COATING A SURFACE | ALLACCEM, INC. | 2011-01-20 | — | — | US | disclosed |
| US-20100004218-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR RENAL THERAPY | ALLACCEM, INC. | 2010-01-07 | — | — | US | disclosed |
| US-20090054528-A1 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | ALLACCEM, INC. | 2009-02-26 | — | — | US | disclosed |
| US-20080275141-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | ALLACCEM, INC. | 2008-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090054528-A1 | Bridged polycyclic compound based compositions for coating oral surfaces in pets | PAICS, SLC16A8, CAD | LMNA 2168/4885RECQL 4649/4885HSPA5 3416/4885 |
| US-20100004218-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR RENAL THERAPY | PKD1, PKD2, PAICS | LMNA 669/4885RECQL 985/4885HSPA5 3636/4885 |
| US-20080275141-A1 | BRIDGED POLYCYCLIC COMPOUND BASED COMPOSITIONS FOR THE INHIBITION AND AMELIORATION OF DISEASE | PKD1, VHL, PKD2 | LMNA 312/4885RECQL 1121/4885HSPA5 2003/4885 |
| US-20110015300-A1 | METHODS AND SYSTEMS FOR COATING A SURFACE | DNMT1, TET2, DNMT3A | LMNA 2708/4885RECQL 1795/4885HSPA5 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.