Phenethylamine

Phenethylamine

SCHEMBL11698137

C=CCN.NCCc1ccccc1

nearest known ligand 0.73

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 3/20 0.73
CYP2A6 P11509 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
TAAR1 Q96RJ0 1/20 0.73
LOXL2 Q9Y4K0 1/20 0.73
MAOA P21397 3/20 0.52
CYP1A2 P05177 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C19 P33261 1/20 0.48
MAOB P27338 3/20 0.48
HTR6 P50406 2/20 0.47
HTR2C P28335 1/20 0.46
SIGMAR1 Q99720 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phenethylamine SCHEMBL27829139 0.86 TAAR1 (0.73) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL1331271 0.85
Phenethylamine SCHEMBL27634208 0.85 HTR2A (1.00) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL1799333 0.85 HTR2A (1.00) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL968 0.85
Phenethylamine SCHEMBL1330939 0.85
Phenethylamine SCHEMBL1332244 0.85
Phenethylamine SCHEMBL8384113 0.83 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL245154 0.83 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2
Phenethylamine SCHEMBL20568335 0.83 HTR2A (0.94) HTR2ACYP2A6SMN1; SMN2TAAR1LOXL2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4013795-A INSECTICIDE, MITICIDE, NEMATOCIDE, FUNGICIDE, BACTERICIDE, RODENTICIDE BAYER AKTIENGESELLSCHAFT (DT) 1977-03-22 US disclosed