Known targets — ChEMBL curated mechanism
ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Phenethylamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A known ✓ | P28223 | 3/20 | 0.94 |
| ▸ | MAOB known ✓ | P27338 | 4/20 | 0.64 |
| ▸ | MAOA known ✓ | P21397 | 3/20 | 0.64 |
| ▸ | HTR6 known ✓ | P50406 | 2/20 | 0.56 |
| ▸ | HTR2C known ✓ | P28335 | 1/20 | 0.54 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.94 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.94 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.94 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.94 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phenethylamine SCHEMBL11664723 | 0.97 | HTR2A (0.89) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 | |
| Phenethylamine SCHEMBL29277512 | 0.97 | HTR2A (0.89) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 | |
| Phenethylamine SCHEMBL16294846 | 0.97 | HTR2A (0.89) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 | |
| Phenethylamine SCHEMBL1332244 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1799333 | 0.97 | HTR2A (1.00) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 | |
| Phenethylamine SCHEMBL27634208 | 0.97 | HTR2A (1.00) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 | |
| Phenethylamine SCHEMBL1331271 | 0.97 | — | — | |
| Phenethylamine SCHEMBL968 | 0.97 | — | — | |
| Phenethylamine SCHEMBL1330939 | 0.97 | — | — | |
| Phenethylamine SCHEMBL5306641 | 0.94 | HTR2A (0.94) | HTR2ALOXL2CYP2A6SMN1; SMN2TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1085 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-122081951-A | Corrosion inhibitor for circulating water of coastal high-chlorine environment steel mill and preparation method thereof | — | 2026-05-26 | — | — | CN | claimed |
| US-20260101625-A1 | PEROVSKITE SOLAR CELL AND ITS PREPARATION | UNIV CITY HONG KONG (HK) | 2026-04-09 | — | — | US | claimed |
| US-20250277127-A1 | PEROVSKITE INK FOR SCALABLE FABRICATION OF EFFICIENT AND STABLE PEROVSKITE MODULES | THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL | 2025-09-04 | — | — | US | claimed |
| CN-120166840-A | Mixed halogen perovskite photovoltaic device based on mesophase regulation and control and preparation method thereof | 河北大学 | 2025-06-17 | — | — | CN | claimed |
| CN-119320637-B | Composition for preparing deep blue light quasi two-dimensional perovskite and application thereof | 五邑大学 | 2025-06-13 | — | — | CN | claimed |
| CN-120076686-A | Perovskite film, preparation method thereof and solar cell | 中国华能集团清洁能源技术研究院有限公司 | 2025-05-30 | — | — | CN | claimed |
| CN-120018742-A | Perovskite surface sequential post-treatment method based on two-dimensional ligand modification materials with different polarities | 武汉理工大学 | 2025-05-16 | — | — | CN | claimed |
| CN-119907603-A | Efficient trans-perovskite solar cell and preparation method thereof | 深圳北理莫斯科大学 | 2025-04-29 | — | — | CN | claimed |
| CN-119907609-A | Solar cell, preparation method thereof, electric equipment and power generation equipment | 天合光能股份有限公司 | 2025-04-29 | — | — | CN | claimed |
| CN-119855350-A | Perovskite solar cell, preparation method thereof, solar cell module and electricity utilization device | 比亚迪股份有限公司 | 2025-04-18 | — | — | CN | claimed |
| EP-1169515-A1 | SIZING COMPOSITION | AKZO NOBEL N.V. (NL) | 2002-01-09 | — | — | EP | claimed |
| WO-2000063493-A1 | SIZING COMPOSITION | AKZO NOBEL N.V. (NL) | 2000-10-26 | — | — | WO | claimed |
| EP-0963484-A1 | SIZING OF PAPER | AKZO NOBEL N.V. (NL) | 1999-12-15 | — | — | EP | claimed |
| EP-0951284-A1 | PHENYLETHYLAMINE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1999-10-27 | — | — | EP | claimed |
| WO-1998033979-A1 | SIZING OF PAPER | AKZO NOBEL N.V. (NL) | 1998-08-06 | — | — | WO | claimed |
| WO-1998026775-A1 | PHENYLETHYLAMINE DERIVATIVES | TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) | 1998-06-25 | — | — | WO | claimed |
| EP-0358856-A2 | Novel insecticidal dibenzoyl-tert-butylcarbanonitrile compounds and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1990-03-21 | — | — | EP | claimed |
| US-4857550-A | Novel insecticidal dibenzoyl-tert-butylcarbazonitrile compounds and method for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1989-08-15 | — | — | US | claimed |
| US-4169943-A | PROCESS FOR THE PREPARATION OF AMINO DERIVATIVES OF N-HETEROCYCLES | SCHERING AKTIENGESELLSCHAFT (DE) | 1979-10-02 | — | — | US | claimed |
| US-4076765-A | MOLDING MATERIALS, CONSTRUCTION MATERIALS | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1978-02-28 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260101625-A1 | PEROVSKITE SOLAR CELL AND ITS PREPARATION | NES, PPOX, SCO2 | HTR2A 3595/4885MAOB 3623/4885MAOA 2855/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.