Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALPG | P10696 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20462899 | 0.96 | HTT (0.47) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL21119444 | 0.89 | HTT (0.50) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL23369925 | 0.81 | L3MBTL1 (0.50) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL35192 | 0.80 | HTT (0.53) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL10297870 | 0.75 | HTT (0.48) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL10431512 | 0.75 | HTT (0.61) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL20462898 | 0.75 | CYP3A4 (0.58) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL518265 | 0.75 | CYP3A4 (0.68) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL752826 | 0.75 | HTT (0.66) | HTTL3MBTL1ALDH1A1GAAMAPT | |
| SCHEMBL755028 | 0.75 | CYP3A4 (0.68) | HTTL3MBTL1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4064104-A | Phosphine oxide flame retardants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4064104-A | Phosphine oxide flame retardants | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-3975447-A | Preparation of aromatic phosphine oxides by reaction of diarylhalophosphine and benzylic halide | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-08-17 | — | — | US | disclosed |