SCHEMBL752826

SCHEMBL752826

O=P(Cc1ccccc1CP(=O)(c1ccccc1)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.66

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
HTT P42858 4/20 0.66
L3MBTL1 Q9Y468 2/20 0.66
ALDH1A1 P00352 6/20 0.55
HPGD P15428 1/20 0.55
GAA P10253 2/20 0.54
MAPT P10636 2/20 0.54
ALPG P10696 1/20 0.54
ALOX12 P18054 1/20 0.54
NPY1R P25929 1/20 0.54
NPY2R P49146 1/20 0.54
NPSR1 Q6W5P4 1/20 0.54
USP2 O75604 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2C19 P33261 1/20 0.52
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10431512 0.85 HTT (0.61) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL10824828 0.85 HTT (0.65) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL29119914 0.85 HTT (0.56) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL5836257 0.82 HTT (0.53) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL11700305 0.81 ALDH1A1 (0.60) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL11863411 0.80 HTT (0.51) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL518265 0.80 CYP3A4 (0.68) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL755028 0.80 CYP3A4 (0.68) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL8009848 0.79 HTT (0.50) HTTL3MBTL1ALDH1A1HPGDGAA
SCHEMBL8010347 0.79 HTT (0.50) HTTL3MBTL1ALDH1A1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 113 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993622-B2 Method of preparing phosphorus-containing flame retardants and their use in polymer compositions LANXESS CORP (US) 2024-05-28 US claimed
EP-3250634-B1 FLAME RETARDANT POLYMER COMPOSITIONS COMPRISING HEAT TREATED PHOSPHORUS COMPOUNDS AND MELAM LANXESS CORP (US) 2022-06-29 EP claimed
US-20220073547-A1 Method of Preparing Phosphorus-Containing Flame Retardants and Their Use in Polymer Compositions LANXESS CORPORATION (US) 2022-03-10 US claimed
EP-3898818-A2 METHOD OF PREPARING PHOSPHORUS-CONTAINING FLAME RETARDANTS AND THEIR USE IN POLYMER COMPOSITIONS LANXESS Corporation (US) 2021-10-27 EP claimed
EP-3898640-A1 METHOD FOR PREPARING READILY PROCESSABLE, THERMALLY-STABLE, PHOSPHORUS-CONTAINING FLAME RETARDANT MATERIAL LANXESS Corporation (US) 2021-10-27 EP claimed
WO-2021076169-A1 METHOD OF PREPARING PHOSPHORUS-CONTAINING FLAME RETARDANTS AND THEIR USE IN POLYMER COMPOSITIONS LANXESS SOLUTIONS US INC. (US) 2021-04-22 WO claimed
WO-2020132075-A2 METHOD OF PREPARING PHOSPHORUS-CONTAINING FLAME RETARDANTS AND THEIR USE IN POLYMER COMPOSITIONS LANXESS SOLUTIONS US INC. (US) 2020-06-25 WO claimed
WO-2020132095-A1 METHOD FOR PREPARING READILY PROCESSABLE, THERMALLY-STABLE, PHOSPHORUS-CONTAINING FLAME RETARDANT MATERIAL LANXESS SOLUTIONS US INC. (US) 2020-06-25 WO claimed
EP-2885308-B1 PHOSPHORUS CONTAINING FLAME RETARDANTS LANXESS SOLUTIONS US INC (US) 2019-04-10 EP claimed
US-10035896-B2 Salts of pyrophosphonic acid as flame retardants LANXESS SOLUTIONS US INC. (US) 2018-07-31 US claimed
EP-3172217-A1 PHOSPHORUS CONTAINING FLAME RETARDANTS Chemtura Corporation (US) 2017-05-31 EP claimed
US-20160215122-A1 Flame Retardant Polymer Compositions Comprising Heat Treated Phosphorus Compounds and Melam LANXESS SOLUTIONS US INC. 2016-07-28 US claimed
US-20160200897-A1 PROCESS STABILIZATION OF POLYMER COMPOSITIONS COMPRISING PHOSPHOROUS CONTAINING FLAME RETARDANTS LANXESS SOLUTIONS US INC. 2016-07-14 US claimed
US-20160032076-A1 SALTS OF PYROPHOSPHONIC ACID AS FLAME RETARDANTS LANXESS SOLUTIONS US INC. 2016-02-04 US claimed
WO-2016014113-A1 PHOSPHORUS CONTAINING FLAME RETARDANTS CHEMTURA CORPORATION (US) 2016-01-28 WO claimed
US-20150307690-A1 HALOGEN FREE HIGH TEMPERATURE POLYAMIDE COMPOSITIONS COMPRISING PHOSPHORUS CONTAINING FLAME RETARDANTS LANXESS SOLUTIONS US INC. 2015-10-29 US claimed
EP-2885308-A1 PHOSPHORUS CONTAINING FLAME RETARDANTS Chemtura Corporation (US) 2015-06-24 EP claimed
US-20150141556-A1 PHOSPHORUS CONTAINING FLAME RETARDANTS CHEMTURA CORPORATION 2015-05-21 US claimed
US-20150031805-A1 Phosphorus Containing Flame Retardants CHEMTURA CORPORATION (US) 2015-01-29 US claimed
WO-2015013370-A1 PHOSPHORUS CONTAINING FLAME RETARDANTS CHEMTURA CORPORATION (US) 2015-01-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11993622-B2 Method of preparing phosphorus-containing flame retardants and their use in polymer compositions PFAS, ARSA, CD79B HTT 4364/4885L3MBTL1 3264/4885ALDH1A1 3021/4885
US-20220073547-A1 Method of Preparing Phosphorus-Containing Flame Retardants and Their Use in Polymer Compositions PPA1, PHOSPHO1, PFAS HTT 1649/4885L3MBTL1 2003/4885ALDH1A1 3027/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.