Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11701431 | 0.84 | CYP2D6 (0.44) | CYP2D6CYP2C19LIPEKMT2APOLB | |
| SCHEMBL11697724 | 0.78 | ALDH1A1 (0.41) | CYP2D6CYP2C19POLBSLC6A2SLC6A4 | |
| SCHEMBL4742849 | 0.74 | CYP2D6 (0.46) | CYP2D6CYP2C19SLC6A2SLC6A4LMNA | |
| SCHEMBL3989090 | 0.73 | CYP2D6 (0.44) | CYP2D6CYP2C19LIPEKMT2APOLB | |
| SCHEMBL13338372 | 0.73 | CYP2D6 (0.47) | CYP2D6CYP2C19LIPEPOLBSLC6A2 | |
| SCHEMBL4500673 | 0.72 | CYP2D6 (0.47) | CYP2D6CYP2C19LIPEKMT2APOLB | |
| SCHEMBL6008374 | 0.71 | HTT (0.44) | MEN1KMT2APOLBLMNATRPM8 | |
| SCHEMBL21884184 | 0.70 | CYP2D6 (0.42) | CYP2D6CYP2C19LIPEKMT2APOLB | |
| SCHEMBL2124908 | 0.69 | TSHR (0.39) | MEN1KMT2ASLC6A2SLC6A4LMNA | |
| SCHEMBL14813491 | 0.69 | POLB (0.39) | CYP2D6CYP2C19MEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4063887-A | HYDROXYAMINE COMPOUND | CELANESE CORPORATION (US) | 1977-12-20 | — | — | US | disclosed |