Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.59 |
| ▸ | NPC1 | O15118 | 4/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.59 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.58 |
| ▸ | APP | P05067 | 2/20 | 0.54 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27670304 | 0.87 | PDPK1 (0.56) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL29778657 | 0.85 | PDPK1 (0.54) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL9718878 | 0.85 | ALDH1A1 (0.65) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL10779720 | 0.83 | ALDH1A1 (0.61) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL21089192 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL21089385 | 0.79 | ALDH1A1 (0.56) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL8530618 | 0.79 | MAPT (0.52) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL29873401 | 0.77 | APP (0.68) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL483414 | 0.77 | APP (0.68) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 | |
| SCHEMBL21089196 | 0.75 | RET (0.49) | SMN1; SMN2KDM4ENPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4039553-A | Certain 2(2'-hydroxyphenyl)benzothiazolo derivatives | GAF CORPORATION (US) | 1977-08-02 | — | — | US | disclosed |
| US-3972875-A | RED FLUORESCENT DYES | GAF CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |