Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 4/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 4/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | MAPT | P10636 | 3/20 | 0.65 |
| ▸ | GAA | P10253 | 2/20 | 0.65 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.42 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | ILK | Q13418 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21089385 | 0.89 | ALDH1A1 (0.56) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL21089192 | 0.89 | ALDH1A1 (0.59) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL10779720 | 0.87 | ALDH1A1 (0.61) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL11698798 | 0.85 | SMN1; SMN2 (0.59) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL906903 | 0.85 | SMN1; SMN2 (0.50) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL21089187 | 0.80 | KDM4E (0.50) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL3247624 | 0.80 | ALDH1A1 (0.47) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL8530618 | 0.79 | MAPT (0.52) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL914476 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 | |
| SCHEMBL29437945 | 0.79 | KDM4E (1.00) | ALDH1A1KDM4ESMN1; SMN2TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5151472-A | Dissolving polyetherimides in a solvent, adding a dianhydride and a diamine, reacting to form a polyamic acid and cyclizing to form a polyimide | GENERAL DYNAMICS CORPORATION, CONVAIR DIVISION (US) | 1992-09-29 | — | — | US | disclosed |