Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.67 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | IDE | P14735 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.46 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514857 | 0.85 | POLB (0.69) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL10919867 | 0.84 | CYP1A2 (0.69) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11694093 | 0.81 | POLB (0.64) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11517061 | 0.80 | POLB (0.63) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11697210 | 0.79 | POLB (0.61) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11517427 | 0.78 | L3MBTL1 (0.52) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11695830 | 0.78 | ATM (0.63) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11515406 | 0.78 | L3MBTL1 (0.52) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11515401 | 0.78 | L3MBTL1 (0.52) | L3MBTL1RXFP1POLBLMNAALDH1A1 | |
| SCHEMBL11696189 | 0.78 | POLB (0.60) | L3MBTL1RXFP1POLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4053475-A | ANTI-ALLERGIC AGENTS | STERLING DRUG INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4008235-A | ANTIALLERGIC | STERLING DRUG INC. (US) | 1977-02-15 | — | — | US | disclosed |